Endocrine conditions & hormone disorders

When a gland makes too much or too little of a hormone, or the body responds to it abnormally, the result is an endocrine disorder. These guides explain common hormone conditions: typical symptoms, how clinicians diagnose them with blood tests and other evaluations, and the general approaches used to manage them.

Symptoms overlap — diagnosis requires testing. Many hormone conditions share non-specific symptoms such as fatigue or weight change. Only a clinician can diagnose a condition using your history, examination, and appropriate tests. Use these guides to learn, not to self-diagnose.

Browse conditions

Hypothyroidism: Underactive Thyroid Explained

A plain-language guide to hypothyroidism: what an underactive thyroid is, common signs, causes, the blood tests used to diagnose it, and how it is managed.

Hyperthyroidism: Overactive Thyroid Explained

A plain-language guide to hyperthyroidism: what an overactive thyroid is, common signs, causes, the blood tests used to diagnose it, and how it is managed.

Hypogonadism (Low Testosterone): A Clear Guide

A plain-language guide to hypogonadism, or low testosterone: what it is, common signs, causes, the blood tests used to diagnose it, and how it is managed.

PCOS: Polycystic Ovary Syndrome Explained

A plain-language guide to PCOS: what polycystic ovary syndrome is, common signs, causes, the blood tests used to diagnose it, and how it is managed.

Menopause: Hormones and Symptoms Explained

A plain-language guide to menopause: what it is, common signs, the hormone changes behind it, how it is recognised, and approaches to managing symptoms.

Cushing's Syndrome Explained: Excess Cortisol

A plain-language guide to Cushing's syndrome: what excess cortisol is, common signs, causes, the tests used to diagnose it, and how it is generally managed.

Addison's Disease (Adrenal Insufficiency) Guide

A plain-language guide to Addison's disease: what adrenal insufficiency is, common signs, causes, the blood tests used to diagnose it, and how it is managed.

Hashimoto's Thyroiditis Explained Clearly

A plain-language guide to Hashimoto's thyroiditis, an autoimmune thyroid condition: common signs, causes, the tests used to diagnose it, and management.

Graves' Disease Explained: Autoimmune Thyroid

A plain-language guide to Graves' disease, an autoimmune cause of an overactive thyroid: common signs, causes, the tests used to diagnose it, and management.

Hyperprolactinemia (High Prolactin) Explained

A plain-language guide to hyperprolactinemia: what high prolactin is, common signs, causes, the blood tests used to diagnose it, and how it is managed.

Type 2 Diabetes & Insulin Explained Clearly

A plain-language guide to type 2 diabetes: what insulin resistance is, common signs, causes, the blood tests used to diagnose it, and how it is managed.

Osteoporosis & Hormones Explained Clearly

A plain-language guide to osteoporosis: what bone thinning is, how hormones affect it, common signs, causes, how it is diagnosed, and how it is managed.

Acromegaly (Excess Growth Hormone) Explained

A plain-language guide to acromegaly: what excess growth hormone is, common signs, causes, the tests and imaging used to diagnose it, and how it is managed.

Hyperparathyroidism Explained: High Calcium

A plain-language guide to hyperparathyroidism: what overactive parathyroid glands are, common signs, causes, the tests used to diagnose it, and management.

Adrenal Insufficiency Explained Clearly

A plain-language guide to adrenal insufficiency: what too little cortisol means, common signs, causes, the blood tests used to diagnose it, and management.

Primary Aldosteronism (Conn's Syndrome) Explained

A plain-language guide to primary aldosteronism, or Conn's syndrome: what it is, common signs, causes, the blood tests used to diagnose it, and management.

Pheochromocytoma Explained: Adrenal Tumour

A plain-language guide to pheochromocytoma: what this adrenal tumour is, common signs, causes, the tests used to diagnose it, and how it is generally managed.

Gynecomastia: Enlarged Male Breast Tissue

A plain-language guide to gynecomastia, or enlarged male breast tissue: what it is, common signs, causes, the tests used to evaluate it, and management.

Hirsutism (Excess Hair Growth) Explained

A plain-language guide to hirsutism, or excess hair growth in women: what it is, common signs, causes, the tests used to evaluate it, and how it is managed.

Prolactinoma: Pituitary Prolactin Tumour Guide

A plain-language guide to prolactinoma: what this pituitary tumour is, common signs, causes, the tests used to diagnose it, and how it is generally managed.

Thyroid Nodules Explained: Lumps in the Thyroid

A plain-language guide to thyroid nodules: what these lumps are, common signs, causes, the tests used to evaluate them, and how they are generally managed.

Goiter (Enlarged Thyroid): Causes and Evaluation

A plain-language guide to goiter, or an enlarged thyroid gland: what it is, common signs, causes, the tests used to evaluate it, and how it is managed.

Hypopituitarism Explained: Underactive Pituitary

A plain-language guide to hypopituitarism: what an underactive pituitary gland is, common signs, causes, the tests used to diagnose it, and how it is managed.

Gestational Diabetes Explained

A plain-language guide to gestational diabetes: what it is, its signs, causes, the blood tests used to find it during pregnancy, and how it is managed.

Diabetes Insipidus Explained

A plain-language guide to diabetes insipidus: what it is, its signs, causes, the tests used to diagnose it, and how this water-balance disorder is managed.

Hypoglycemia (Low Blood Sugar) Explained

A plain-language guide to hypoglycemia: what low blood sugar is, its signs, common causes, how it is evaluated with blood tests, and how it is managed.

Metabolic Syndrome Explained

A plain-language guide to metabolic syndrome: what this cluster of risk factors is, its signs, causes, how it is identified with tests, and how it is managed.

Premature Ovarian Insufficiency Explained

A plain-language guide to premature ovarian insufficiency: what it is, its signs, causes, the hormone tests used to evaluate it, and how it is managed.

Congenital Adrenal Hyperplasia (CAH) Explained

A plain-language guide to congenital adrenal hyperplasia: what this inherited adrenal condition is, its signs, causes, how it is diagnosed, and management.

Pituitary Adenoma Explained

A plain-language guide to pituitary adenoma: what this gland tumour is, its signs, causes, the hormone and imaging tests used to find it, and management.

Thyroid Cancer: An Overview of Signs and Tests

A plain-language overview of thyroid cancer: what it is, common signs, causes and risk factors, the tests used to evaluate it, and how it is generally managed.

Insulinoma Explained: A Rare Pancreatic Tumour

A plain-language guide to insulinoma: what this rare insulin-producing pancreatic tumour is, its signs, causes, the tests used to diagnose it, and how it is managed.

Precocious (Early) Puberty: Signs and Tests

A plain-language guide to precocious puberty: what early puberty is, its signs, causes, the hormone tests used to evaluate it, and how it is generally managed.

Delayed Puberty Explained: Signs and Testing

A plain-language guide to delayed puberty: what late puberty is, its signs, causes, the hormone tests used to evaluate it, and how it is generally managed.

Turner Syndrome: Hormonal and Endocrine Aspects

A plain-language guide to the hormonal aspects of Turner syndrome: what it is, common signs, causes, the tests used to evaluate it, and how it is generally managed.

Klinefelter Syndrome: Hormonal and Endocrine Aspects

A plain-language guide to the hormonal aspects of Klinefelter syndrome: what it is, common signs, causes, the tests used to evaluate it, and how it is managed.

Adrenal Incidentaloma Explained: Tests and Care

A plain-language guide to adrenal incidentaloma: what an unexpected adrenal mass is, why it matters, the hormone tests used to evaluate it, and how it is managed.

Sources

  1. MedlinePlus (U.S. National Library of Medicine). Endocrine Diseases. https://medlineplus.gov/endocrinediseases.html
  2. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). https://www.niddk.nih.gov/